Complex Trait Consortium

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Questions or comments? Please contact
Robert W. Williams

Related Sites
The Jackson Laboratory

The Mouse Brain Library
The WebQTL Project
CGB Center of Genomics and Bioinformatics

18th Annual Meeting of the Complex Trait Community in collaboration with the Rat Genomics Community.
The meeting will now run virtually September 1-3, 2021.
Registration and Abstract submission is now open

  • Virtual meeting from Manchester, UK.

Webinar - Data structure, disease risk, GXE, and causal modeling
Friday, November 20th at 9am PDT/ 11pm CDT/ 12pm EDT

Presented by Dr. Rob Williams Professor and Chair
Department of Genetics, Genomics, and Informatics
University of Tennessee Health Science Center


CTC -- The Complex Trait Consortium Mailing List
In general we would like to encourage use of the CTC LISTSERV to:

  • Discuss research plans and results
  • Devise better ways to share resources
  • Post questions and answers on particular technical problems pertaining to QTL mapping and complex trait analysis
  • Announce and plan scientific meetings
  • Share papers and preprints of broad interest
  • Provide pointers and commentary on Internet resources

To see the collection of prior postings to the list, visit the CTC Archives:

Delayed until June 2021 18th Annual Meeting of the Complex Trait Community in collaboration with the Rat Genomics Community. Delayed until June 2021: CTC-Rat Genome meeting will still be in Manchester but summer 2021 due to current pandemic.

June 8 to 11, 2019 Complex Traits Consortium / Rat Genomics 17th Annual Meeting La Jolla, California on the University of California San Diego campus from Saturday, June 8 to Tuesday, June 11, 2019.

June 20 to 22, 2018 16th Annual Meeting of the Complex Trait Community in collaboration with the Rat Genomics Community June 20 to 22, 2018 Glasgow, UK.

25th August - 1st September 2017 Summer School in Systems Medicine 25th August - 1st September 2017, Frauenchiemsee, Germany

June 13 to 17, 2017 15th Annual Meeting of the Complex Trait Community in collaboration with the Rat Genomics Community June 13 to 17, 2017 Memphis, TN USA.

June 8-11, 2015 Complex Trait Community 14th annual meeting in Portland, Oregon, USA, June 8-11, 2015

May 19-22, 2014 13th Annual Meeting of the Complex Trait Community in Berlin, Germany, May 19-22, 2014

May 29-31, 2013 Complex Trait Community 12th annual meeting Madison, Wisconsin May 29-31, 2013

June 12-15, 2012 11th Annual Meeting of the Complex Trait Community in Paris, France June 12-15, 2012.

June 22-25, 2011 10th Annual Meeting of the Complex Trait Community in Washington, DC USA (June 22-25, 2011)
Hosted by the GSA Genetics Society of America

May 7-10, 2010 Complex Trait Community 9th annual meeting Chicago, Illinois USA 2010

February 22-27, 2009 Quantitative Genetics & Genomics
Hotel Galvez Galveston, TX Chair: Daniel Pomp Vice Chair: Peter M. Visscher

May 2-5, 2009 8th Annual Meeting of the Complex Trait Community in Manchester, 2nd-5th May 2009
[More Info and Registration]

May 31 - June 3, 2008 7th Annual Meeting of the Complex Trait Consortium in Montreal Canada (May 31 - June 3, 2008)

May 26-29, 2007 6th Annual Meeting of the Complex Trait Consortium in Braunschweig, Germany (May 26-29, 2007)
[More Info and Registration]

May 6-10, 2006 5th Annual Meeting of the Complex Trait Consortium
(Chapel Hill, North Carolina)
[More Info and Registration] [List of Attendees] [Gallery]

June 26-29, 2005 4th Annual Meeting of the Complex Trait Consortium (Groningen, the Netherlans)
Meeting Home Page [List of Attendees] [Gallery]

July 6-9, 2004 Complex Trait Consortium 2004 (Bar Harbor, ME)
3rd Annual Conference

July 1-3, 2003 (2nd Annual CTC Meeting Oxford, July 1-3, 2003)
2nd Annual CTC Meeting

November 17, 2002 (CTC Satellite Meeting of the IMGC San Antonio, TX)
CTC Satellite Meeting of the IMGC

May 15-17, 2002 (1st Annual CTC Meeting Memphis, TN)
1st Annual CTC Meeting

Recent Publications
All Publications | Archive
A Collaborative Cross for High-Precision Complex Trait Analysis
CTC Workgroup Report (pdf)
Read Review

Genetic dissection of a behavioral quantitative trait locus shows that Rgs2 modulates anxiety in mice
Nature Genetics November 2004 (pdf)
Print PDF

Scientists Dream of 1001 Complex Mice
Geneticists want to create 1000 new lines of inbred mice to help them sort out the genes behind complex diseases such as diabetes and cancer.

The Collaborative Cross: Rationale, Implementation, and Costs
A presentation at NIH, March 17, 2004
Read word or pdf document

Mouse Genetics Concepts and Applications
By Lee M. Silver
Read Review

CTC 2001-2005
See All Abstracts
Poster Session Abstracts and Computer Demonstration:
  • Genetics of skin tumor promotion susceptibility
  • Candidate gene approach in two Arab Israeli cohorts confirms and refines schizophrenia susceptibility locus on chromosome 6Q23
  • An integrated approach to managing and displaying quantitative trait loci data
  • Finding quantitative trait genes that influence mouse behaviour
  • The genomes of recombinant inbred lines
  • Polymorphism and qtl detection using oligo-based microarrays
  • Characterization of obesity phenotypes in chromosome 2 congenic strains
  • Substitution mapping identifies two distinct blood pressure quantitative trait loci at the q-terminus of rat chromosome 3 in congenic substrains derived from dahl rats

  • CTC 2004
    Power-point Presentations

  • The genomes of recombinant inbred lines
  • From QTL to QTG: Are we getting closer?

    Current Archive

  • Collaboration Group

    Collaborative Cross Workgroup [Restricted Web]
    A flexible, powerful, secure, yet simple web-based collaboration platform.

    Set of abstracts, papers for the poster and computer demo sessions.

    Power-Point Presentations
    Set of abstracts, papers for the poster and computer demo sessions.

    All research papers

    November 20, 2007
    Meeting report of the 6th annual meeting of the complex trait consortium.
    Department of Experimental Mouse Genetics, Helmholtz Centre for Infection Research and University of Veterinary Medicine Hannover, Inhoffenstr. 7, D-38124, Braunschweig, Germany,
    PMID: 17906895 [PubMed - in process]

    February 20, 2006
    Meeting report for the 4th Annual Complex Trait Consortium Meeting: From QTLs to Systems Genetics.
    Department of Genetics, CB#7264, University of North Carolina, Chapel Hill, NC, 27599, USA, The fourth annual meeting of the Complex Trait Consortium (CTC) was held in Groningen, the Netherlands on June 26-29, 2005. This meeting, which set a new attendance record, followed three previous and highly successful meetings. The focus at this meeting was on continued resource development and the exiting new field of systems genetics, the integration and anchoring of multi-dimensional data-types to underlying genetic variation. A new aspect at the meeting was the three-minute, 'come see my poster' presentations that generated significant interaction at the poster sessions. If the 2005 meeting is an indicator of things to come, future meetings promise to offer even more exciting research efforts to integrate high-throughput biological measurements with genetic variation to unravel the mechanisms responsible for inter-individual variation.

    August 12, 2005
    Mouse Engineering. Making Better Models for Complex Common Disease
    Complex Trait Consortium, an international effort by 300 geneticists to create a population of mice that mimics the human population when studying disease as well as drug reactions.
    Most science is still done by looking at a single gene within a single mouse strain, for two reasons: Until recently it's not been possible to study how multiple genes work in concert. Also, federal funding is geared toward specific goals that can be reached in a couple of years, which means that lone gene in isolation gets the money. Read Article , by Scott Shepard. Memphis Business Journal.

    April 16, 2005
    Mouse Inbred Line Genotype Data
    Please note that a preliminary release and analysis of the mouse genotype data for the strains submitted to us by the CTC is now available from, The data look OK based on our initial analyses, but if you see anything wrong or missing please let us know.
    In summary, we got good data for 13377 SNPs that mapped onto Build33 of the mouse genome (there are a few more good SNPs which will be positioned shortly). There are data for 477 contributed DNAs.
    The haplotype block structures of the RIL panels in the set are interesting. [Many thanks to all those who contributed DNAs and SNP data ].

    Wellcome Trust Centre
    Mouse Inbred Line Genotype Data
    This page contains information related to our project to genotype Recombinant Inbred Lines and Inbred Lines across 15360 SNPs. 2019 modify this page Page maintained by R. Williams | A. Centeno Last updated December 12, 2020.