CTC-RG 19th Annual Meeting University of Colorado. September 29th and 30th 2022.
The 19th Annual Meeting of the Complex Trait Community, in collaboration with the Rat Genomics Community, will be held at the University of Colorado Anschutz Medical Campus as a hybrid meeting on September 29 th and 30 th 2022.
The meeting will be held in the Education 2 South Building on campus
| Index | Type | Time (MDT) | Title | Speaker | Affiliation |
|---|---|---|---|---|---|
| 01 | 8:00 am | Registration open/Light Breakfast | |||
| 02 | 9:00 am | Plenary Session #1 | |||
| 03 | Leveraging public data with machine learning to study complex diseases | Arjun Krishnan, PhD | University of Colorado Anschutz Medical Campus | ||
| 04 | 10:00 am | Discussion | |||
| 05 | 10:30 am | BREAK | |||
| 06 | Virtual | 10:45 am | Spontaneous nonsense mutation in Tuft1 (tuftelin 1) gene is associated with amelioration of glucose and lipid metabolism in the BXH6 subline of rat recombinant inbred strains | Michal Pravenec | Institute of Physiology, Czech Academy of Science |
| 07 | Virtual | 11:00 am | Identifying modulators of optic nerve numbers and health in glaucoma using systems genetics | Aman Kumar | University of Tennessee Health Science Center |
| 08 | Virtual | 11:15 am | A novel pre-clinical model identifies genetic modifiers of triple negative breast cancer risk and progression | David Ashbrook | University of Tennessee Health Science Center |
| 09 | Virtual | 11:30 am | Replicated loci that modulate lifespan and longevity in females of the BXD family on Chr 1 and Chr 3 | Suheeta Roy | University of Tennessee Health Science Center |
| 10 | 11:45 am | Lunch - box lunches provided | |||
| 11 | In-person | 12:45 pm | Distinct genetic mechanism associated with phenotype response in chow-fed versus high fat diet-fed mice | Cody Cousineau | University of Michigan School of Public Health |
| 12 | In-person | 1:00 pm | Cocaine addiction is associated with long-term changes in gene regulation, metabolic pathways, and GABAergic inhibition within the amygdala | Jessica Zhou | University of California San Diego |
| 13 | In-person | 1:15 pm | Attribution of incentive salience to reward cues is genetically associated with other addiction-related traits in outbred hetergeneous stock rats | Christopher King | University at Buffalo |
| 14 | In-person | 1:30 pm | Genome-wide association study in a rat model of temperament identifies multiple loci for exploratory locomotion and anxiety-like traits | Apurva Chitre | University of California San Diego |
| 15 | In-person | 1:45 pm | Identification of actionable target genes that regulate breast cancer progression by genetic linkage analysis in HER2/Neu Transgenic Diversity Outbred (DO) F1 mice | Jennifer Jacob | Wayne State University |
| 16 | 2:00 pm | BREAK | |||
| 17 | Virtual | 2:15 pm | Multiple genome viewer (MGV): a new tool for visualization and comparison of multiple annotated genomes | Michelle Perry | The Jackson Laboratory |
| 18 | Virtual | 2:30 pm | Initial effort in generating a rat pangenome | Flavia Villani | University of Tennessee Health Science Center |
| 19 | Virtual | 2:45 pm | Which mouse multiparental population is right for your study? The Collaborative Cross inbred strains, their F1 hybrids, or the Diversity Outbred population | Gregory Keele | The Jackson Laboratory |
| 20 | In-person | 3:00 pm | Hybrid genotyping pipeline on Lc-WGS and ddGBS sequences for heterogeneous stock rats | Denghui Chen | University of California San Diego |
| 21 | In-person | 3:15 pm | The Rat Genome Database resources for de novo rat strain assemblies | Jennifer Smith | Medical College of Wisconsin |
| 22 | 3:30 pm | BREAK | |||
| 23 | Virtual | 3:45 pm | Genetic analysis of multi-omic data identifies drivers of protein phosphorylation | Gary Churchill | The Jackson Laboratory |
| 24 | Virtual | 4:00 pm | Increasing power in inbred strain association mapping by recognizing variance heterogeneity | William Valdar | University of North Carolina at Chapel Hill |
| 25 | Virtual | 4:15 pm | The regulatory landscape of multiple brain regions in outbred heterogeneous stock rats | Dan Munro | University of California San Diego & Scripps Research |
| 26 | In-person | 4:30 pm | A novel quantitative trait locus implicates Msh3 in the propensity for genome-wide short tandem repeate expansions in mice | Cynthia Wu | University of California San Diego |
| 27 | In-person | 4:45 pm | Polygenic transcriptome risk scores can translate genetic results between species | Abraham Palmer | University of California San Diego |
| 28 | 5:00 pm | POSTER SESSION | |||
| 29 | Genetic Loci Associated with Skeletal Response to PTH Therapy | Douglas Adams | University of Colorado Anschutz Medical Campus | ||
| 30 | PhenoMiner: RGD's quantitative phenotype data repository has data update and data mining tool improvements | Mary Kaldunski | Medical College of Wisconsin | ||
| 31 | PhenoGen: HRDP Transcriptome Data and API | Spencer Mahaffey | University of Colorado Anschutz Medical Campus | ||
| 32 | Characterization of polymorphic short tandem repeats and their association with phenotypes in HS rats | Ryan Eveloff | University of California San Diego | ||
| 33 | Improving de novo genome assemblies of the HXB/BXH family of inbred strains using Hi-C data | Panjun Kim | University of Tennessee Health Science Center | ||
| 34 | Completion of genomic rat variants analysis of the Hybrid Rat Diversity Panel | Monika Tutaj | Medical College of Wisconsin | ||
| 35 | 6:00 pm | Optional Group Dinner |
| Index | Type | Time (MDT) | Title | Speaker | Affiliation |
|---|---|---|---|---|---|
| 01 | 8:00 am | Registration open/Light Breakfast | |||
| 02 | 9:00 am | Developing a Model of Cannabis Psychopharmacology and Harm Reduction: Empirical Investigations Using Legal Market Products | L. Cinnamon Bidwell | University of Colorado Boulder | |
| 03 | 10:00 am | BREAK | |||
| 04 | Virtual | 10:15 am | Dissecting the mechanisms of indirect genetic effects in outbred mouse population | Helene Tonnele | Centre for Genomic Regulation of Barcelona |
| 05 | Virtual | 10:30 am | Alternative splicing of osteopontin in CRISPR/Cas9 knock out rats | Cara Trivett | University of Glasgow |
| 06 | Virtual | 10:45 am | Incorporating strain-specific variance into genome-wide inbred strain mapping for zero-inflated phenotypes | Teresa McGee | University of North Carolina Chapel Hill |
| 07 | In-person | 11:00 am | Scalable in vitro model using scRNA-seq to generate cell-type specific transcriptome profiles of osteogenic cells | Luke Dillard | University of Virginia |
| 08 | In-person | 11:15 am | Adjusting for cis-regulatory variation in gene expression data can improve biological network analysis in model organisms | Jack Pattee | University of Colorado Anschutz Medical Campus |
| 09 | 11:30 am | Lunch - box lunches provided | |||
| 10 | Virtual | 12:30 pm | Genetic analysis of CNS autoimmunity using the diversity of the Collaborative Cross reveals unique phenotypes and mechanisms | Emily Holt | University of Vermont |
| 11 | Virtual | 12:45 pm | OPEN | ||
| 12 | Virtual | 1:00 pm | Genetic regulation of heart mitochondrial proteome influencing heart function | Karthickeyan Chella Krishnan | University of Cincinnati |
| 13 | Virtual | 1:15 pm | Gene-by-treatment QTL mapping to dissect genetic susceptibility to severe coronavirus disease | Ellen Risemberg | University of North Carolina Chapel Hill |
| 14 | 1:30 pm | BREAK | |||
| 15 | Virtual | 1:45 pm | Network-based analysis predicts interacting genetic modifiers from a mapping study of multiple absence epilepsy mouse models | Montana Lara | University of Vermont |
| 16 | Virtual | 2:00 pm | GRK5 is required for adipogenesis through activation of ERK pathway | Mary Seramur | Wake Forest University |
| 17 | Virtual | 2:15 pm | Adcy3 knock-out rats show increased adiposity without changes in behavioral phenotypes | Mackenzie Roberts | Wake Forest University |
| 18 | In-person | 2:30 pm | Classifying the discrete epigenetic environment involved in drug-seeking behavior | Carl Litif | University of Wyoming |
| 19 | 2:45 pm | BREAK | |||
| 20 | 3:00 pm | A genetic basis for oxidative stress response variation | Callan O'Connor | The Jackson Laboratory | |
| 21 | 3:15 pm | Genetic background in the rat impacts metabolic outcomes of post-wean BPF exposure | Valerie Wagner | Medical College of Wisconsin, USA | |
| 22 | 3:30 pm | Structural equation modeling uncovers candidate genes for cocaine's conditioned effects in heterogeneous stock rats | Joel Leal-Gutierrez | University of California San Diego | |
| 23 | 3:45 pm | Genome-wide association studies of human and rat body mass index converge on a conserved molecular network | Brittany Leger | University of California San Diego | |
| 24 | 4:00 pm | Genome-wide association study finds multiple loci associated with intraocular pressure in HS rats | Oksana Polesskaya | University of California San Diego | |
| 25 | 4:15 pm | Closing Remarks |